Targeted Nalmefene With Simple Medical Management in the Treatment of Heavy Drinkers: A Randomized Double-Blind Placebo-Controlled Multicenter Study

Julkaistu 7.7.2016. Päivitetty 28.1.2022.

Julkaisun nimi:

Tekijä:

Karhuvaara, S., Simojoki, K., Virta, A., Rosberg, M., Löyttyniemi, E., Nurminen, T., Kallio, A. & Mäkelä, R.

Ingressi:

This multisite, randomized double-blind study investigated targeted nalmefene in reducing heavy drinking.

Julkaisukieli:

Englanti

Julkaisumuoto:

Muu julkaisu

Liittyy hankkeeseen:

Alkoholi

Julkaisuvuosi:

2007

Julkaisun tiedot:

Alcohol Clin Exp Res. 2007 Apr 19

Lyhyt kuvaus:

This multisite, randomized double-blind study investigated targeted nalmefene in reducing heavy drinking. Specialized alcohol treatment centers and private general practices enrolled 403 subjects (328 men, 75 women). Subjects were instructed to take nalmefene 10 to 40 mg (n=242) or placebo (n=161) when they believed drinking to be imminent. After 28 weeks, 57 subjects from the nalmefene group continued into a 24-week randomized withdrawal extension. Concomitant psychosocial intervention was minimal and no treatment goals were imposed.

Nalmefene appears to be effective and safe in reducing heavy drinking, even when accompanied by minimal psychosocial support.

Keywords: Alcohol drinking, Medicine, Nalmefene, Alcoholism, Drug Therapy, Rehabilitation

Avain-/asiasanat: alkoholi, lääketiede, nalmefeeni, alkoholiriippuvuus, alkoholiriippuvuuden hoito, kuntoutus

Julkaisun teema-alue:

01. alkoholi

08. hoito ja kuntoutus

Linkki julkaisuun:

avaa linkki tästä

https://pubmed.ncbi.nlm.nih.gov/17451401/

Pääteema:

Päihteet

Julkaisutyyppi: