Bioavailability of Buprenorphine from Crushed and Whole Buprenorphine (Subutex) Tablets

Tutkimus

Buprenorphine (Subutex) is the most abused opioid in Finland. In order to curb the abuse potential of this drug, many treatment centers and prisons crush Subutex tablets before administering them to patients. To date, there are no published studies comparing the efficacy and bioavailability of crushed and whole Subutex tablets.